The response to Covid-19 saw dramatic advancements in the development of life-saving vaccines. These changes have created an opportunity to make preventable diseases history. Now is the time to transform the global health infrastructure, making it more equitable and also ensuring the world is prepared for the next pandemic. This means harnessing the potential of and demand for next-generation vaccines and preventative injectables. The potential rewards are huge, with at least 10 million deaths a year attributable to preventable diseases.
One Shot sets out a roadmap to combat preventable diseases worldwide that draws on innovations in vaccines and preventative injectables and builds on progress made in response to Covid-19. This vision for a disease-prevention programme that is “always on” would save millions of lives and billions of dollars, addressing health inequalities and leading to more prosperous, healthy and resilient societies.