Transplant recipients are rejecting their new organ after receiving a vaccination against Covid-19, adding an additional challenge for the vaccinated population, according to the new study published in the Journal of Clinical Medicine.
A group of 18 health experts and researchers from Japan conducted a study to systematically evaluate and characterise the currently reported cases of acute corneal graft rejection after being injected with a Covid “vaccine.” A rejection graft occurs when the recipient’s immune system rejects tissue from a donor, in this case, the cornea.
Allograft is the transplant of an organ or tissue from one individual to another of the same species with a different genotype. For example, a transplant from one person to another, but not an identical twin, is an allograft. Allografts account for many human transplants, including those from cadaveric, living-related, and living unrelated donors.
Compared to other organs, the cornea has a relatively low rate of allograft rejection due to its “immune privilege.” This fact prompted the Japanese researchers to examine the recent rise in corneal graft rejection following Covid injections.