Why did APHIS decide to do this study? APHIS supports a One Health approach to address animal diseases, including SARS-CoV-2. White-tailed deer are susceptible to SARS-CoV-2, are abundant in the United States (approximately 30 million*), and often come into close contact with people. Given these factors, we felt it prudent to further investigate SARS-Cov-2 in wild deer. Studying the susceptibility of certain mammals, such as deer, to the SARS-CoV-2 virus helps to identify species that may serve as reservoirs or hosts for the virus. It also helps us understand the origin of the virus and predict its impacts on wildlife and the risks of cross-species transmission.