There is only one sickness, one disease and one treatment. The one sickness and one disease is the over-acidification of the blood and then interstitial fluids due to an inverted way of living, eating, drinking, breathing, thinking, feeling and believing. There are six major contributing factors that lead to the declining acidic pH of the body fluids. As the pH of the body fluids become compensated by these six contributing factors and the body cell membranes and genetic material begin to degenerate the cells release exosomes as a defense to activate and support the lymphocytes to release oxygen species or antioxidants to reduce the acidic loads stored in the interstitial fluids of the Interstitium. The one treatment is to support the immune system with increased amounts of reduced oxygen (O-) and reduced hydrogen (H-) to restore the alkaline design of the body fluids, open up the channels of elimination in order to remove dietary, metabolic, respiratory and environmental toxic acidic waste held in the interstial fluids of the Interstitium and thus restoring health, energy and vitality to the body.
Exosomes are membrane bound extracellular vesicles (EVs) that are produced in the endosomal compartment of most eukaryotic cells. The multivesicular body (MVB) is an endosome defined by intraluminal vesicles (ILVs) that bud inward into the endosomal lumen. If the MVB fuses with the cell surface (the plasma membrane), these ILVs are released as exosomes. In multicellular organisms, exosomes and other EVs are present in cells that make up tissues and can also be found in biological fluids including intracellular fluids, intravascular fluids, interstitial fluids, urine, and cerebrospinal fluid. They are also released in vitro by cultured cells into their growth medium.
Since the size of exosomes is limited by that of the parent MVB, exosomes are generally thought to be smaller than most other EVs, from about 30 to 150 nanometres (nm) in diameter: around the same size as many lipoproteins but much smaller than cells. Compared with EVs in general, it is becoming more clear that exosomes do have unique characteristics or functions and can be separated or distinguished effectively from other EVs. EVs including exosomes carry markers of cells of origin and have specialized functions in physiological processes, from coagulation and intercellular signaling to acidic waste management of the intravascular and interstitial fluids of the Interstitium – the largest organ of the human body.